AZ7188

Ligand id: 9586

Name: AZ7188

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 36.1
Molecular weight 262.11
XLogP 3.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
PAR2 Hs Antagonist Antagonist 5.2 pIC50 - 1
pIC50 5.2 (IC50 6x10-6 M) [1]
Description: Antagonism of SLIGRL-NH2-induced IP1 formation.