clodronic acid

Ligand id: 9605

Name: clodronic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 134.68
Molecular weight 243.89
XLogP -2.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at transporters
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
Vesicular nucleotide transporter Hs Inhibitor Inhibition 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.56x10-8 M) [1]
Description: Using a quantitative transport assay system involving proteoliposomes containing only expressed and purified protein.