Ligand id: 9650

Name: dagrocorat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 62.22
Molecular weight 494.22
XLogP 10.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Glucocorticoid receptor Agonist Partial agonist 8.9 pIC50 - 1
pIC50 8.9 (IC50 1.31x10-9 M) [1]
Description: Measured in a glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay.