dagrocorat

Ligand id: 9650

Name: dagrocorat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 62.22
Molecular weight 494.22
XLogP 10.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Glucocorticoid receptor Agonist Partial agonist 8.9 pIC50 - 1
pIC50 8.9 (IC50 1.31x10-9 M) [1]
Description: Measured in a glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay.