erythromycin-A

Ligand id: 1456

Name: erythromycin-A

Abbreviated name: EM-A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 7
Topological polar surface area 193.91
Molecular weight 733.46
XLogP 1.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Erythromycin is used to treat bacterial infections.
Mechanism Of Action and Pharmacodynamic Effects
Erythromycin interferes with bacterial survival by inhibiting translation and protein assembly by binding to bacterial 50S ribosomal subunits.