bupivacaine

Ligand id: 2397

Name: bupivacaine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 32.34
Molecular weight 288.22
XLogP 4.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Bupivacaine is used as a local anaesthetic
Mechanism Of Action and Pharmacodynamic Effects
Bupivacaine binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, preventing depolarization and the generation and conduction of nerve impulses.