ibuprofen

Ligand id: 2713

Name: ibuprofen

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 37.3
Molecular weight 206.13
XLogP 5.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Ibuprofen is used widely for its analgesic and antipyretic actions.
Mechanism Of Action and Pharmacodynamic Effects
Ibuprofen reversibly inhibits cyclooxygenase (COX) enzymes 1 and 2, causing a reduction in synthesis of pro-inflammatory prostaglandins.
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