triamcinolone

Ligand id: 2870

Name: triamcinolone

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View more information in the IUPHAR Pharmacology Education Project: triamcinolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 115.06
Molecular weight 394.18
XLogP 0.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Triamcinolone is used for its antiinflammatory or immunosuppressive actions in many conditions. For example, oral triamcinolone is used to treat conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, and breathing disorders. This drug is also used topically as an anti-inflammatory and anti-pruritic agent. Injectable forms of the drug may be used to reduce intra-articular joint pain, stiffness and swelling associated with rheumatoid and osteoarthritic arthritis, bursitis, epicondylitis, and tenosynovitis.
Mechanism Of Action and Pharmacodynamic Effects
Please see DrugBank link on the Summary tab of this ligand page for an overview of the mechanism of action of triamcinolone.
External links