scopolamine

Ligand id: 330

Name: scopolamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 62.3
Molecular weight 303.15
XLogP 2.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
An antimuscarinic drug with central nervous system effects, scopolamine has many clinical used including for the treatment of motion sickness, postoperative nausea and vomiting, irritable bowel syndrome and gastrointestinal spasms.
Mechanism Of Action and Pharmacodynamic Effects
Interferes with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system.
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