Ligand id: 4838

Name: metolazone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 100.88
Molecular weight 365.06
XLogP 2.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
A diuretic used in the treatment of congestive heart failure and hypertension.
Mechanism Of Action and Pharmacodynamic Effects
For an overview of the mechanism of action of metolazone, please see the entry of DrugBank linked to from this ligand page.