fasudil

Ligand id: 5181

Name: fasudil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 70.68
Molecular weight 291.1
XLogP 0.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved only in China and Japan. Used to treat cerebral vasospasm [8]. May be effective in pulmonary hypertension [3] and may improve memory in Alzheimer's disease [5].
Mechanism Of Action and Pharmacodynamic Effects
Fasudil has vasodilatory effects [2].