naproxen

Ligand id: 5230

Name: naproxen

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 46.53
Molecular weight 230.09
XLogP 3.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also used in pain relief in the treatment of primary dysmenorrhea.
Mechanism Of Action and Pharmacodynamic Effects
Naproxen inhibits cyclooxygenase enzymes COX-1 and COX-2 leading to a reduction in inflammation.
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