carbamazepine

Ligand id: 5339

Name: carbamazepine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 48.02
Molecular weight 236.09
XLogP 4.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Carbamazepine is used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. It is also used to treat bipolar disorder.
Mechanism Of Action and Pharmacodynamic Effects
The mechanism of action of carbamazepine is complex and poorly defined, but appears to involve inhibition of sodium channel α subunits.