betaxolol

Ligand id: 549

Name: betaxolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 50.72
Molecular weight 307.21
XLogP 2.77
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Oral administration of betaxolol is used to treat hypertension. In the UK, glaucoma and ocular hypertension are the only approved indications for the use of betaxolol.
Mechanism Of Action and Pharmacodynamic Effects
Betaxolol selectively blocks catecholamine stimulation of β1-adrenoceptors in the heart and vascular smooth muscle, resulting in reduced heart rate, cardiac output, and blood pressure.
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