metoprolol

Ligand id: 553

Name: metoprolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 50.72
Molecular weight 267.18
XLogP 2.03
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the management of heart conditions including acute myocardial infarction, angina pectoris, heart failure, and in hypertension. Also used in the treatment of supraventricular and tachyarrhythmias and the prevention of migraine.
Mechanism Of Action and Pharmacodynamic Effects
Antagonist of beta adrenergic receptors. Blockage of these receptors in the heart leads to decreased heart rate, cardiac output and blood pressure.