vinblastine

Ligand id: 6851

Name: vinblastine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 154.1
Molecular weight 810.42
XLogP 4.01
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer, breast cancer, head and neck cancer, and testicular cancer. It is also used to treat Langerhans cell histiocytosis.
Mechanism Of Action and Pharmacodynamic Effects
Causes cell cycle arrest by inhibiting microtubule assembly.
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