Ligand id: 7107

Name: acebutolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 91.15
Molecular weight 336.2
XLogP 2.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat hypertension.
Mechanism Of Action and Pharmacodynamic Effects
Acebutolol anatgonises β1-adrenoceptors in the sympathetic system. This prevents the receptors from processing signals from eondogenous epinephrine and norepinephrine resulting in decreased force of heart contractions and lowered heart rate. See the DrugBank link for further details.
External links