Ligand id: 7133

Name: brompheniramine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 16.13
Molecular weight 318.07
XLogP 4.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat the symptoms of many allergic conditions, and rhinitis associated with colds and flu.
Mechanism Of Action and Pharmacodynamic Effects
Brompheniramine blocks the action of endogenous histamine at the histamine H1 receptor. This drug may also have anticholingeric/antimuscarinic action which is likely to contribute to the drug's side effects, which include drowsiness, dry mouth and throat and increased heart rate.