meclofenamic acid

Ligand id: 7219

Name: meclofenamic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 49.33
Molecular weight 295.02
XLogP 4.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat muscular pain, arthritis and dysmenorrhea. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity. It also has antipyretic action and stabilises mast cells and reduces their degranulation.