mivacurium

Ligand id: 7243

Name: mivacurium

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 30
Topological polar surface area 144.9
Molecular weight 1028.56
XLogP 6.43
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used as a muscle relaxant during anaesthetic procedures, and to facilitate tracheal intubation in patients requiring mechanical ventilation.
Mechanism Of Action and Pharmacodynamic Effects
Mivacurium antagonises the activation of nicotinic acetylcholine receptor complexes at the motor end-plate. This blocks nerve action potential and impulse transmission between the nerves and muscles.
External links