piroxicam

Ligand id: 7273

Name: piroxicam

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View more information in the IUPHAR Pharmacology Education Project: piroxicam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 111.47
Molecular weight 331.06
XLogP 3.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat rheumatoid and osteoarthritis, primary dysmenorrhoea and postoperative pain.
Mechanism Of Action and Pharmacodynamic Effects
As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity. Piroxicam also affects leukocyte migration to inflammatory sites. See the DrugBank link for further details.
External links