trimethobenzamide

Ligand id: 7614

Name: trimethobenzamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 69.26
Molecular weight 388.2
XLogP 2.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Trimethobenzamide is prescribed to treat and prevent nausea and vomiting caused by gastroenteritis or other illnesses [1], medications or surgery [2].
Mechanism Of Action and Pharmacodynamic Effects
The precise MMOA of this drug remains elusive, but it is believed to affect the chemoreceptor trigger zone (CTZ) of the medulla oblongata.
External links