compound 6a [PMID: 18942826]

Ligand id: 8744

Name: compound 6a [PMID: 18942826]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 87.49
Molecular weight 167.02
XLogP 0.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
Co-crystallisation reveals that compound 6a binds KDM4A (JMJD2A in the article) between the β-sheets of its double stranded β-helix [1].