rotigotine

Ligand id: 941

Name: rotigotine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 51.71
Molecular weight 315.17
XLogP 4.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of Parkinson's disease and restless legs syndrome.
Mechanism Of Action and Pharmacodynamic Effects
Dopamine receptor agonist which works by mimicking the effect of neurotransmitter dopamine. Rotigotine is delivered continuously through the skin using patches.
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