prednisolone

Ligand id: 2866

Name: prednisolone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 360.19
XLogP 1.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Prednisolone ia an approved drug for the diseases listed below. It may also be used to treat relapses in multiple sclerosis.
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Glucocorticoid drug used to treat many inflammatory condtions including RA.
Crohn's disease Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206
Glucocorticoid drug used to treat many inflammatory condtions including CD.
Systemic lupus erythematosus Disease Ontology: DOID:9074
OMIM: 152700
Orphanet: ORPHA536
Glucocorticoid drug used to treat many inflammatory condtions including SLE.
Ulcerative colitis Disease Ontology: DOID:8577
OMIM: 266600
Orphanet: ORPHA771
Glucocorticoid drug used to treat many inflammatory condtions including UC.
Asthma Disease Ontology: DOID:2841
OMIM: 600807
Glucocorticoid drug used to treat many inflammatory condtions including asthma.
Chronic obstructive pulmonary disease Disease Ontology: DOID:3083
Glucocorticoid drug used to treat many inflammatory condtions including COPD.
Autoimmune thrombocytopenic purpura Disease Ontology: DOID:8924
OMIM: 188030
Orphanet: ORPHA3002
Glucocorticoid drug used to treat many inflammatory condtions including ATP.