rofecoxib

Ligand id: 2893

Name: rofecoxib

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: rofecoxib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 68.82
Molecular weight 314.06
XLogP 4.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Osteoarthritis Disease Ontology: DOID:8398
Withdrawn from US market due to safety concerns.
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Withdrawn from US market due to safety concerns.