alvelestat

Ligand id: 6476

Name: alvelestat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 122.64
Molecular weight 545.13
XLogP 4.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Graft versus host disease A Phase 2 clinical candidate for bronchiolitis obliterans syndrome resulting from chronic GVHD.
Diabetes mellitus, type 2 Disease Ontology: DOID:9352
A Phase 2 clinical candidate predicted to exhibit a useful effect on T2D-associated inflammation.
Chronic obstructive pulmonary disease Disease Ontology: DOID:3083
A Phase 2 clinical candidate for COPD.