idelalisib

Ligand id: 6741

Name: idelalisib

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 86.8
Molecular weight 415.16
XLogP 4.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Chronic lymphocytic leukemia Disease Ontology: DOID:1040
OMIM: 151400
Orphanet: ORPHA67038
Approved in combination with rituximab for CLL. Also used to treat relapsed small lymphocytic leukemia (SLL).
non-Hodgkin lymphoma Disease Ontology: DOID:0060060
OMIM: 605027
Approved specifically for relapsed follicular B-cell non-Hodgkin lymphoma.