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Synonyms: Arcalyst® | IL-1 Trap | interleukin-1 Trap
rilonacept is an approved drug (FDA (2008), EMA (2009))
Compound class:
Peptide or derivative
Comment: Rilonacept is a fusion protein consisting of the binding domains of the IL-1 receptor (IL-1R) and the IL-1 receptor accessory protein (IL-1RAcP) linked to the Fc portion of human IgG1.
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| Immunopharmacology Disease | |||
| Disease | X-Refs | Comment | References |
| Muckle-Wells syndrome |
OMIM:
191900 Orphanet: ORPHA575 |
Approved drug for Muckle-Wells syndrome. | |
| Familial cold autoinflammatory syndrome 1; FCAS1 |
OMIM:
120100 Orphanet: ORPHA47045 |
Approved drug for FCAS1. | |
| CINCA syndrome |
OMIM:
607115 Orphanet: ORPHA1451 |
Approved drug for CINCA syndrome. | |
