leflunomide

Ligand id: 6825

Name: leflunomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 55.13
Molecular weight 270.06
XLogP 3.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Leflunomide acts as a disease modifying anti-rheumatic drug (DMARD).
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
A DMARD approved for active RA.