teriflunomide

Ligand id: 6844

Name: teriflunomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 73.12
Molecular weight 270.06
XLogP 3.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Teriflunomide inhibits pyrimidine synthesis, resulting in antiproliferative and anti-inflammatory effects (immunomodulatory).
Immunopharmacology Disease
Disease X-Refs Comment References
Relapsing-remitting multiple sclerosis Disease Ontology: DOID:2378
A RR-MS treatment initiated under specialist supervision.