peginterferon alfa-2b   Click here for help

GtoPdb Ligand ID: 7462

Synonyms: PegIntron® | Sylatron®
Approved drug Immunopharmacology Ligand
peginterferon alfa-2b is an approved drug (EMA (2000), FDA (2001))
Compound class: Peptide or derivative
Comment: Peginterferon alfa-2b is a pegylated interferon protein. Conjugation with polyethylene glycol (PEG) is a strategy commonly used to protect peptide drugs from in vivo proteolytic breakdown to increase their biological half-life and duration of action.
Peginterferon alfa-2b is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Immunopharmacology Comments
An immunostimulatory drug used in Hepatitis C infected patients and to treat melanoma after surgical resection.