maraviroc

Ligand id: 806

Name: maraviroc

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 63.05
Molecular weight 513.33
XLogP 7.43
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Maraviroc-induced CCR5 blockade failed to show clinical efficacy in RA.
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Maraviroc-induced CCR5 blockade failed to show clinical efficacy in RA clinical trial.