CGI1746

Ligand id: 8066

Name: CGI1746

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 90.98
Molecular weight 579.28
XLogP 7.15
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
CGI1746-mediated inhibition of BTK suppresses B cell- and myeloid cell-mediated arthritis [1].