amelubant

Ligand id: 8463

Name: amelubant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 100.87
Molecular weight 538.25
XLogP 9.67
No. Lipinski's rules broken 2

Molecular properties generated using the CDK
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
 No progress in development beyond Phase 2 trial in RA.
Asthma Disease Ontology: DOID:2841
OMIM: 600807
 No progress in development beyond Phase 2 trial in asthma.
Chronic obstructive pulmonary disease Disease Ontology: DOID:3083
 No progress in development beyond Phase 2 trial in COPD.