compound 18c [PMID: 25901531]

Ligand id: 9227

Name: compound 18c [PMID: 25901531]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 106.95
Molecular weight 410.08
XLogP 3.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Compound 18C has biological activity in several cellular models of inflammation as well as cancer [1].