CGI560

Ligand id: 9264

Name: CGI560

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 71.32
Molecular weight 461.22
XLogP 8.92
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
CGI560 is a potent, reversible BTK inhibitor, that was tested preclinically for potential clinical utility in inflammatory diseases and B cell malignancies.