deflazacort

Ligand id: 9477

Name: deflazacort

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 102.26
Molecular weight 441.22
XLogP 1.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Autoimmune thrombocytopenic purpura Disease Ontology: DOID:8924
OMIM: 188030
Orphanet: ORPHA3002
Approved corticosteroid that can be prescribed for ATP.
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Approved corticosteroid that can be prescribed for RA.
Crohn's disease Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206
Approved corticosteroid that can be prescribed for CD.
Systemic lupus erythematosus Disease Ontology: DOID:9074
OMIM: 152700
Orphanet: ORPHA536
Approved corticosteroid that can be prescribed for SLE.
Ulcerative colitis Disease Ontology: DOID:8577
OMIM: 266600
Orphanet: ORPHA771
Approved corticosteroid that can be prescribed for UC.
Juvenile idiopathic arthritis- systemic OMIM: 604302
Approved corticosteroid that can be prescribed for sJIA.
Sarcoidosis Disease Ontology: DOID:11335
Approved corticosteroid that can be prescribed for sarcoidosis.
Duchenne muscular dystrophy Disease Ontology: DOID:11723
OMIM: 19518854
Deflazacort was approved by the US FDA in 2017 as a treatment for DMD.