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Molecular properties generated using the CDK
|Guide to Malaria Pharmacology Comments|
|BRD3444 has promising activity against multiple lifecycle stages of the Plasmodium parasite .
Potential Target/Mechanism Of Action: Correlation of purified cPheRS IC50 values against parasite growth inhibition assays for a range of analogues, together with genetic evidence, indicate that PfcPheRS is the relevant molecular target of this bicyclic azetidine series .