[125I]CGP 64213

Ligand id: 1076

Name: [125I]CGP 64213    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Topological polar surface area 166
Molecular weight 646.13
XLogP 3.45
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Galvez T, Urwyler S, Pr├ęzeau L, Mosbacher J, Joly C, Malitschek B, Heid J, Brabet I, Froestl W, Bettler B et al.. (2000)
Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit.
Mol. Pharmacol.57 (3): 419-26. [PMID:10692480]
2. Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W, Bettler B. (1997)
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors.
Nature386: 239-246. [PMID:9069281]