3-APMPA

Ligand id: 1080

Name: 3-APMPA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 73.13
Molecular weight 137.06
XLogP -0.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Froestl W, Mickel SJ. (1997)
Chemistry of GABAB modulators.  in  The GABA Receptors
Edited by Enna SJ, Bowery NG Humana Press. 271-296  [ISBN:0896034585]
2. Wood MD, Murkitt KL, Rice SQ, Testa T, Punia PK, Stammers M, Jenkins O, Elshourbagy NA, Shabon U, Taylor SJ, Gager TL, Minton J, Hirst WD, Price GW, Pangalos M. (2000)
The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
Br J Pharmacol131: 1050-1054. [PMID:11082110]