A-349821

Ligand id: 1217

Name: A-349821

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Topological polar surface area 97.36
Molecular weight 320.15
XLogP 0.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Esbenshade TA, Fox GB, Krueger KM, Baranowski JL, Miller TR, Kang CH, Denny LI, Witte DG, Yao BB, Pan JB, Faghih R, Bennani YL, Williams M, Hancock AA. (2004)
Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.
Biochem Pharmacol68: 933-945. [PMID:15294456]