pyrilamine

Ligand id: 1227

Name: pyrilamine

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View more information in the IUPHAR Pharmacology Education Project: mepyramine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R. (2002)
A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.
J Pharmacol Exp Ther302: 328-336. [PMID:12065734]
2. Ratnala VR, Swarts HG, VanOostrum J, Leurs R, DeGroot HJ, Bakker RA, DeGrip WJ. (2004)
Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor.
Eur J Biochem271: 2636-2646. [PMID:15206929]