compound 17 [PMID: 17125263]

Ligand id: 1306

Name: compound 17 [PMID: 17125263]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 51.79
Molecular weight 485.13
XLogP 7.08
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Tavares FX, Al-Barazanji KA, Bishop MJ, Britt CS, Carlton DL, Cooper JP, Feldman PL, Garrido DM, Goetz AS, Grizzle MK, Hertzog DL, Ignar DM, Lang DG, McIntyre MS, Ott RJ, Peat AJ, Zhou HQ. (2006)
6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.
J Med Chem49: 7108-7118. [PMID:17125263]