3,5-DHPG

Ligand id: 1367

Name: 3,5-DHPG

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 103.78
Molecular weight 183.05
XLogP -2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Lavreysen H, Janssen C, Bischoff F, Langlois X, Leysen JE, Lesage AS. (2003)
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.
Mol Pharmacol.63: 1082-1093. [PMID:12695537]
2. Mutel V, Ellis GJ, Adam G, Chaboz S, Nilly A, Messer J, Bleuel Z, Metzler V Malherbe Schlaeger EJ, Roughley BS, Faull RL, Richards JG. (2000)
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
J Neurochem.75: 2590-2601. [PMID:11080213]