BAY 367620

Ligand id: 1381

Name: BAY 367620

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 26.3
Molecular weight 278.13
XLogP 6.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Carroll FY, Stolle A, Beart PM, Voerste A, Brabet I, Mauler F, Joly C, Antonicek H, Bockaert J, Muller T, Pin JP, Prezeau L. (2001)
BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity.
Mol Pharmacol.59: 965-973. [PMID:11306677]
2. Lavreysen H, Janssen C, Bischoff F, Langlois X, Leysen JE, Lesage AS. (2003)
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.
Mol Pharmacol.63: 1082-1093. [PMID:12695537]