Ro67-4853

Ligand id: 1387

Name: Ro67-4853

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 64.63
Molecular weight 325.13
XLogP 4.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Knoflach F, Mutel V, Jolidon S, Kew JN, Malherbe P, Vieira E, Wichmann J, Kemp JA. (2001)
Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site.
Proc Natl Acad Sci U S A., 98: 13402-13407. [PMID:11606768]