CPPHA

Ligand id: 1423

Name: CPPHA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 86.71
Molecular weight 406.07
XLogP 4.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. O'Brien JA, Lemaire W, Wittmann M, Jacobson MA, Ha SN, Wisnoski DD, Lindsley CW, Schaffhauser HJ, Rowe B, Sur C, Duggan ME, Pettibone DJ, Conn PJ, Williams DL Jr. (2004)
A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain.
J Pharmacol Exp Ther.309: 568-577. [PMID:14747613]