acipimox

Ligand id: 1596

Name: acipimox

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: acipimox

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 77.13
Molecular weight 154.04
XLogP -0.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Soga T, Kamohara M, Takasaki J, Matsumoto S, Saito T, Ohishi T, Hiyama H, Matsuo A, Matsushime H, Furuichi K. (2003)
Molecular identification of nicotinic acid receptor.
Biochem Biophys Res Commun303: 364-369. [PMID:12646212]
2. Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB. (2003)
Molecular identification of high and low affinity receptors for nicotinic acid.
J Biol Chem278: 9869-9874. [PMID:12522134]