ethyketazocine

Ligand id: 1610

Name: ethyketazocine

Abbreviated name: EKC

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 40.54
Molecular weight 299.19
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Meng F, Xie GX, Thompson RC, Mansour A, Goldstein A, Watson SJ, Akil H. (1993)
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Proc Natl Acad Sci U S A90: 9954-9958. [PMID:8234341]
2. Yasuda K, Raynor K, Kong H, Breder CD, Takeda J, Reisine T, Bell GI. (1993)
Cloning and functional comparison of κ and δ opioid receptors from mouse brain.
Proc. Natl. Acad. Sci. U.S.A.90: 6736-6740. [PMID:8393575]
3. Zhu J, Luo LY, Li JG, Chen C, Liu-Chen LY. (1997)
Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.
J Pharmacol Exp Ther282: 676-684. [PMID:9262330]