BX 667

Ligand id: 1767

Name: BX 667

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 2
Rotatable bonds 16
Topological polar surface area 164.67
Molecular weight 586.26
XLogP 2.42
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Post JM, Alexander S, Wang YX, Vincelette J, Vergona R, Kent L, Bryant J, Sullivan ME, Dole WP, Morser J, Subramanyam B. (2008)
Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization.
Thromb Res, 122: 533-540. [PMID:18539312]